THCv is a propyl analog of Δ9-THC Its journey begins as cannabigerovarin acid (CBGVA), then gradually synthesizes into tetrahydrocannabivarin (THCVA) throughout the plant’s maturation. Other cannabinoids follow this same path of transformation. For example, cannabigerol acid (CBGA) transforms into CBDA and THCA.
After decarboxylation, THCVA undergoes a final conversion during which the molecular acid component is lost. Heat is gradually applied during decarboxylation, also known as decarbing. Decarbing may take place throughout the extraction process, during incineration, or during vaporization (smoking, vaping). When THCVA is heated, the molecule changes into THCv.
Advantages of THCv D9
9-Tetrahydrocannabivarin (THCV) is a cannabis-derived molecule that differs from more popular cannabinoids like 9-Tetrahydrocannabinol in several ways (THC). The absence of psychotropic effects is the primary benefit of THCV over THC. In trials on rodents, THCV reduces hunger, boosts satiety, and regulates energy metabolism, making it a therapeutically effective treatment for weight loss, managing obesity, and treating type 2 diabetes.
A naturally occurring THC analog is THCV. THCV is a non-psychoactive, neutral CB1 antagonist/reverse agonist and, depending on the dose, may operate as either an agonist or antagonist at the CB2 receptors, in contrast to THC, which is psychoactive and an agonist at the CB1 and CB2 receptors.
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